This study aims to explore employers’ attitudes and perceptions in hiring and retaining people with physical disabilities. Semi-structured interviews were carried out with eleven human resource managers working in the private sector of Islamabad. Transcripts comprising participants verbatim were analyzed using Thematic Analysis and a descriptive approach. The reliability of the research was established by ensuring credibility, dependability, transferability, and conformability. Inter-rater reliability was found satisfactory. Findings show six major themes namely employers’ attitude, policy awareness and implementation, perceived concerns and challenges by employers, barriers to employment of people with disability (PWD), provision of reasonable accommodation and, career development and retention policy. The research findings indicate that human resource managers generally have socially desirable, favorable attitudes towards the employment of people with disabilities. However, in-depth exploration indicated either attitudinal barriers or apprehensions to hire PWD due to the lack of resources and limitations in policy implementation. Findings show that small and medium-sized organizations face greater challenges in hiring and retaining PWD. Further, a dire need for governmental and legislative support to the employers is highlighted. Implications of research findings have been discussed.