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Canarium odontophyllum Miq. (Dabai) Leaf Phytoextracts and Their Medicinal Properties

Muhammad Wahizul Haswan Abdul Aziz, Siti Fathiah Masre, Dayang Fredalina Basri and Ahmad Rohi Ghazali

Pertanika Journal of Science & Technology, Volume 30, Issue 3, July 2022

DOI: https://doi.org/10.47836/pjst.30.3.20

Keywords: Canarium odontophyllum Miq., dabai, flavonoids, medicinal properties, phytoextracts, terpenoids

Published on: 25 May 2022

Canarium odontophyllum Miq., renowned locally as “dabai,” is an endemic plant in Sarawak, Malaysia. Most people, especially in rural areas, consume this plant to maintain their health. A few medicinal studies have investigated C. odontophyllum Miq.’s biological properties to substantiate its use as nutraceuticals and health supplements. Crude extracts from C. odontophyllum Miq. demonstrated various medicinal properties, including antibacterial, antimalarial, antioxidant, anticancer, antidiabetic, and antihypertensive. In addition, numerous phytoextracts studies have revealed the existence of a variety of beneficial compounds, including flavonoids, tannins, and terpenoids. However, despite various biological activities of C. odontophyllum Miq., there is currently no analysis summarizing the medicinal properties of its leaf. Thus, this short communication attempts to narrate the medicinal properties of C. odontophyllum Miq. leaf and their phytoextracts responsible. In conclusion, we summarized C. odontophyllum Miq. leaf promising therapeutic effects with their phytoextracts and a step closer to developing it as potential nutraceuticals and health supplements to fulfill social interest.

  • Basri, D. F., & Nor, N. H. M. (2014). Phytoconstituent screening and antibacterial activity of the leaf extracts from Canarium odontophyllum Miq. American Journal of Plant Sciences, 5, 2878-2888. https://dx.doi.org/10.4236/ajps.2014.519303

  • Basri, D. F., & Sandra, V. (2016). Synergistic interaction of methanol extract from Canarium odontophyllum Miq. leaf in combination with oxacillin against methicillin-resistant Staphylococcus aureus (MRSA) ATCC 33591. International Journal of Microbiology, 7, Article 5249534. https://doi.org/10.1155/2016/5249534

  • Basri, D. F., Heng, K. Y., Meng, C. K., & Ghazali, A. R. (2014). Screening of antioxidant phytoextracts of Canarium odontophyllum Miq. leaves in vitro. IOSR Journal of Pharmacy, 4(12), 1-6. http://iosrphr.org/papers/v4i12/Version-3/A041230106.pdf

  • Basri, D. F., Rahman, N. S., Ali, S. S., & Zainalabidin, S. (2018). The vasorelaxant effect of Canarium odontophyllum Miq. (dabai) extract in rat thoracic aorta. Egyptian Journal of Basic and Applied Sciences, 5, 75-79. https://doi.org/10.1016/j.ejbas.2017.11.004

  • Basri, D. F., Shabry, A. S. M., & Meng, C. K. (2015). Leaves extract from Canarium Odontophyllum Miq. (dabai) exhibits cytotoxic activity against human colorectal cancer cell HCT 116. Natural Products Chemistry & Research, 3, 1-4. https://doi.org/10.4172/2329-6836.1000166

  • Basri, D. F., Shamsuddin, N. A. M., & Ishak, S. F. (2016). Time-kill assay and post-antibiotic effect of acetone extract of Canarium odontophyllum leaves against methicillin-resistant Staphylococcus aureus (MRSA). International Journal of Current Medical and Pharmaceutical Research, 2(9), 630-635.

  • Bhatnagar, S., & Das, P. (2007). Antimalarial activity in tropical plants: A review. Journal of Herbs, Spices & Medicinal Plants, 13(1), 103-132. https://doi.org/10.1300/J044v13n01_09

  • Budin, S. B., Kumar, S., Warif, N. M. A., Saari, S. M., & Basri, D. F. (2018). Protective effect of aqueous extracts from Canarium odontophyllum Miq. leaf on liver in streptozotocin-induced diabetic rats. Life Sciences, Medicine and Biomedicine, 2(1), 1-5. https://doi.org/10.28916/lsmb.2.1.2018.5

  • Craig, W. J. (1999). Health-promoting properties of common herbs. The American Journal of Clinical Nutrition, 70(3), 491s-499s. https://doi.org/10.1093/ajcn/70.3.491s

  • Ghazali, A. R., Khairuddin, F. M., Nagapan, T. S., & Basri, D. F. (2017). The mutagenicity and antimutagenicity of Canarium odontophyllum (dabai) acetone leaves extracts. Journal of Agricultural Science, 9, 62-72. https://doi.org/10.5539/jas.v9n13p62

  • Ishak, S. A., Azmi, F. F., Zahari, A., & Basri, D. F. (2020). Antimalarial activity of Canarium odontophyllum leaf extracts against erythrocytes infected with Plasmodium berghei NK65 using Plasmodium Lactate Dehydrogenase (pLDH) and SYBR Green 1 fluorescence assay. SSRN Electronic Journal, 1-23. http://dx.doi.org/10.2139/ssrn.3747151

  • Karak, P. (2019). Biological activities of flavonoids: An overview. International Journal of Pharmaceutical Sciences and Research, 10(4), 1567-1574.

  • Latiff, A., Faridah, H. I., & Zakri, A. H. (2000). The importance of biodiversity conservation research and collaboration in the ASEAN: A view from Asean scientists. In Proceedings of the First Scientific Planning Conference & Report of the Second Scientific Experts Meeting (SEC) Meeting of ARCBC (Vol. 24). Kuala Lumpur, Malaysia.

  • Mahato, S. B., & Sen, S. (1997). Advances in triterpenoid research, 1990-1994. Phytochemistry, 44(7), 1185-1236. https://doi.org/10.1016/S0031-9422(96)00639-5

  • Pajari, A. M., Päivärinta, E., Paavolainen L., Vaara, E., Koivumäki, T., Garg, R., Heiman-Lindh, A., Mutanen, M., Marjomäki. V., & Ridley, A. J. (2016). Ellagitannin-rich cloudberry inhibits hepatocyte growth factor induced cell migration and phosphatidylinositol 3-kinase/AKT activation in colon carcinoma cells and tumors in Min mice. Oncotarget, 7(28), 43907-43923. https://doi.org/10.18632/oncotarget.9724

  • Saari, S. M., Basri, D. F., Budin, S. B., & Warif, N. M. A. (2017). Effects of Canarium odontophyllum leaves on plasma glucose and T lymphocyte population in streptozotocin- induced diabetic rats. Saudi Journal of Biological Sciences, 24(2), 320-323. https://doi.org/10.1016/j.sjbs.2015.09.032

  • Shamsuddin, N. A. M., Zin, N. M., & Basri, D. F. (2018). An assessment of the acetone extract from the leaves of Canarium odontophyllum (Miq.) for antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA). Malaysian Journal of Microbiology, 14(6), 601- 605. https://dx.doi.org/10.21161/mjm.1461821.

  • Singh, B., Singh, J. P., Kaur, A., & Singh N. (2018). Phenolic compounds as beneficial phytochemicals in pomegranate (Punica granatum L.) peel: A review. Food Chemistry, 261, 75-86. https://doi.org/10.1016/j.foodchem.2018.04.039

  • Zou, B., Ge, Z. Z., Zhang, Y., Du, J., Xu, Z., & Li, C. M. (2014). Persimmon tannin accounts for hypolipidemic effects of persimmon through activating of AMPK and suppressing NF- kappaB activation and inflammatory responses in high-fat diet rats. Food and Function, 5(7), 1536- 1546. https://doi.org/10.1039/c3fo60635j

ISSN 0128-7702

e-ISSN 2231-8534

Article ID

JST-2869-2021

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