Failure of pancreas can cause uncontrolled blood glucose levels in the body. This research focuses on type 1 diabetes patients who depend on external insulin injection. The Hovorka model was used as the mathematical model in the development of control algorithm for artificial pancreas. However, the model showed a lack of interaction on selected parameters and variables in its glucose-insulin dynamic system. An improvement on the Hovorka equations was done, but no work was carried out to simulate the proposed equations. The objectives of this study are to simulate the modified Hovorka equations using MATLAB and to compare the simulation results between the reference and modified ones. This study showed better interaction among all variables and parameters on its glucose-insulin dynamic system using the modified equations compared to the original equations. The lower administered amount of insulin, U_t at 16.7mU/min and 20mU/min could regulate the blood glucose level at normoglycemic condition throughout the study.