To ensure reliable and efficient operations of encryption and hash codes, a unique approach of formulating a security key from Deoxyribonucleic acid (DNA) of an individual is presented in this paper. The fusion of DNA sequence with Linear Congruential Generator (LCG) sequence ensures uniqueness in the keys generated and eradicates the problem of duplicate keys. The obtained key is significant due to its optimum length and robust algorithm. Simulation results reveal that keys produced thus pass the criteria of being random, by a significant coefficient value. Uniqueness is verified through avalanche test, which assures generation of a unique key every time.