Social acceptance by people without disabilities has been identified as one of the prominent obstacles faced by people with disabilities (PWD) in their involvement in physical activity. To further apprehend this issue, the present study aims to examine the factors that influence public acceptance towards PWD involvement in physical activity. An exploratory model of public acceptance was developed using key antecedents identified from previous literature. Using convenience sampling technique, a total of 444 responses were collected from the public (without disabilities), who were exercising at four urban public recreation parks located in Klang Valley. Structural Equation Modeling (SEM) approach was used to analyze the data collected. The findings revealed the importance of five prominent antecedents that were personality, attitudes, exposure, ethnicity and subjective norms in explaining public acceptance towards physical activity participation of the disabled. Subjective norms were identified as the most important factor in influencing public acceptance. Additionally, public attitude also depicted a mediating role in the relationship between exposure and public acceptance. A pertinent contribution of the study was the introduction of the extended model of public acceptance developed from integrated framework of theory of reasoned action (TRA), social learning theory, and big five model (BFM), which contributed better understanding of public acceptance towards disabled people. Further understanding of these factors towards PWD involvement in physical activity is essential to promote social inclusion in building a better community for the PWD. Implications of the result for future practices and directions of research are discussed.