The present study aims to assess the validity and reliability of the Persian version of the Infidelity Questionnaire (INFQ). Specifically, INFQ assesses the possible elements of sexual and emotional infidelity. The instrument was translated through the back-translation strategy and revised by three panels. The validity and reliability of the INFQ were examined in the current study. Results showed that the Persian version of the infidelity questionnaire has reasonable internal consistency. The validity was achieved when the results showed that there were significant relationships between personality issues and seduction, leisure activities and social background, and between parenting, social background and sexuality. These findings proved the validity and applicability of the Persian version of INFQ in the Iranian community.