User-centred design applies to processes in which end-users influence how a design takes shape. Usability engineering is now in the direction of the user-centred approach. This article addresses a review of its restrictions and challenges. Problems will be focused on healthcare as it is a critical system that may cause medical errors which can lead to the patient's injury or death. Through user interaction with healthcare devices/software, many usability problems have been identified including poor legibility, feature clutter, poorly distinguished alarms or alerts, lack of intelligent design, poor feedback on system behaviour, no provision for online help, poor support in local languages and right-handed design. Analysis of the usability evaluation technique was conducted to remedy the identified problems and meet the usability objective.