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DinuclearCo(II) and Zn(II) Azomethine Complexes: Physicochemical and Antibacterial Studies

Hadariah Bahron, Siti Najihah Abu Bakar, Siti Solihah Khaidir and Mastura Mohtar

Pertanika Journal of Tropical Agricultural Science, Volume 25, Issue S, August 2017

Keywords: Antibacterial, azomethine, binuclear, X-Ray crystallography

Published on: 26 Feb 2018

A symmetrical azomethine ligand L was synthesised from a reaction of m-phenylenediamine and o-vanillin in 1:2 molar ratio. Dinuclear complexes of Zn2L2 and Co2L2 have been successfully isolated and characterised through 1H NMR, IR and magnetic moment. The x-ray crystal structure of Zn2L2 showed that the two Zn(II) nuclei were coordinated to two L moieties through the phenolic oxygen and imine nitrogen atoms, forming a slightly distorted tetrahedral geometry around the Zn(II) centres. When coordinated to metal centres, the signature n(C=N) of Lat 1616 cm-1 experienced a shift towards lower wave numbers of 1573-1613 cm-1. The Zn(II) complex was diamagnetic whereas the Co2L2 complex was paramagnetic with 3 unpaired electrons having µ eff = 4.07 B.M. An antibacterial screening against methicillin resistant Staphylococcus aureus (MRSA) revealed that the activity of the complexes was more pronounced than that of the uncoordinated L. The complex Zn2L2 revealed the lowest MIC value of 0.56 µg/µl MIC, indicating that it was a better bactericides than Co2L2 and L, in that order.

ISSN 1511-3701

e-ISSN 2231-8542

Article ID

JST-S0407-2017

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