Eco-design is an advanced method for product and process to achieve sustainability. For sustainability, manufacturing companies should contemplate and encourage eco-design products and processes. Brass-ware manufacturing involved excessive energy consumption and material wastage, which makes the process unsustainable. The purpose of this study is to develop a systematic-innovation methodology for the eco-design process in brass-ware manufacturing by considering the eco-efficiency parameters based on Quality Function Deployment (QFD) approach and Theory of Inventive Problem Solving (TRIZ) tools. QFD is used for translating customers’ requirements into manufacturing standards. TRIZ laws are used to solve the eco-contradiction matrix, which finds solutions to make the process eco-efficient and sustainable. On solving the eco-contradiction matrix generic solution is obtained such as ‘31 Porous Materials’, ‘15 Dynamics’, ‘10 Preliminary Action’, and ‘40 Composite Material’. The application of the proposed method has been demonstrated by a case study of the brass-ware manufacturing process in India. This method may be useful and used as a potent tool for design engineers to invent new, robust, and eco-friendly products and processes.