The author sought to verify occupational stress among Thai immigrant employees aged 20 years or older in Bangkok, Thailand and to determine the variables (e.g. working conditions, workloads, job securities and wages) associated with occupational stress among Thai immigrant employees in Bangkok. Five hundred Thai immigrant employees in Thailand's capital, Bangkok, were interviewed. Occupational stress was assessed using the Thai Job Content Questionnaire (Thai-JCQ), Thai version, which was applied using the Job Demand Control (JDC) model by Karasek. Data analysis was undertaken using a path diagram. The results showed that the variables could explain the occupational stress change by 26.6%. Working conditions, workload and job security have a direct effect on occupational stress with standardised regression weights of 0.309, 0.204 and 0.172 (p-value<0.01), respectively. Moreover, workload has indirect relationship on occupational stress with standardised regression weights of 0.062 (p-value<0.01). In contradiction, wages did not have any significance. In conclusion, working conditions have the most direct relationship on occupational stress. A suggestion should be that a study, using qualitative methods, is undertaken to further understand its links to the creation of health policy.