The research in this paper discusses about the development and validation of a novel, cost effective, simple, reproducible and accurate UV-spectrophotometric method to estimate naratriptan hydrochloride in bulk as well as pharmaceutical formulations. Naratriptan hydrochloride was analyzed at 223 nm in simulated saliva (pH 6.8) and phosphate buffer (pH 7.4). Linearity was present in the concentration range of 1-40 µg/ml for both media. The method was validated as per different parameters according to International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) guidelines of Q2 (R1). The suggested method was successfully used for the analysis of naratriptan hydrochloride in-house oral film formulation as linearity values for the same were found to be 1-40µg/mL. The results revealed the suitability of the technique for the estimation of naratriptan hydrochloride in the oral films for its accuracy, precision, and reproducibility.