Soybean is the one most important oil-producing crop in Nigeria and the world. Genotype by environment interaction has been a major hindrance to effective selection and production. This study was conducted to determine the response of 43 soybean accessions to three environments to identify accessions that are adapted to the specific location and those that have wide adaptation. The 43 accessions were collected from the International Institute for Tropical Agriculture (IITA), Ibadan, Nigeria, and tested during the growing seasons of the years 2013, 2014, and 2015 in Ibadan. The data were analyzed using the additive main effects and multiplicative interaction (AMMI) and genotype main effect plus genotype-byenvironment interaction (GGE) biplot methods. The AMMI analysis showed significant G x E interaction and identified accessions TGm-107, TGm-1200, and TGm-802 as the most desirable genotypes, whereas, TGm-868 and TGm-1209 were the least stable. The first two PC of the GGE analysis were able to capture 88.8% of the total variability due to G x E interaction. Accessions TGm-107, TGm-1200, and TGm-802 were the best performing and stable accessions due to their shortest projections in GGE biplot.